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Mapping Human Stem Cells with Genome-Scale CRISPRi
1+ hour, 1+ min ago (724+ words) In the ever-evolving landscape of genomics and stem cell biology, the recent publication in Nature Biotechnology heralds a transformative leap forward in our understanding of human pluripotency....
U2 AF1 mutations rescue deleterious exon skipping induced by KRAS mutations | Nature Genetics
9+ hour, 35+ min ago (1722+ words) Nature Genetics (2026) Cite this article This study does not report custom code or software. Software packages used are described within the appropriate Methods subsections and in the Reporting Summary. Yoshida, K. et al. Frequent pathway mutations of splicing machinery in myelodysplasia....
Synthetic Human Chromosomes Explained
17+ hour, 45+ min ago (223+ words) From synthetic chromosomes and recoded genomes to next-generation gene therapies and engineered cells, discover how genome-scale engineering is redefining the possibilities of biology while reshaping the future of medicine and biotechnology. Image Credit: Anusorn Nakdee / Shutterstock. com Similarly, in regenerative…...
Indiana University Biologists Discover Molecular Mechanism Driving Spread
16+ hour, 31+ min ago (544+ words) of Antibiotic Resistance Genes in Bacteria Bioengineer. org...
Scientists Unlock How Jellyfish Heal Wounds in Minutes
17+ hour, 37+ min ago (535+ words) In the realm of regenerative biology, few organisms captivate scientists quite like the jellyfish species Clytia hemisphaerica. A decade ago, Jocelyn Malamy, an associate professor specializing in Molecular Genetics and Cell Biology at the University of Chicago, embarked on a…...
Hierarchical Artificial Intelligence Maps Long-Range DNA Signals Controlling RNA Splicing
1+ day, 6+ hour ago (64+ words) [IMAGE] Eurek Alert! A hierarchical Transformer model analyzes DNA sequences spanning up to 100, 000 base pairs, linking distant regulatory elements with splice-site activity while highlighting biologically important regions through attention maps. Credit must be given to the creator. More on this…...
Why the temporal dimension matters in cellular signalling - Nature Cell Biology
1+ day, 8+ hour ago (396+ words) Nature Cell Biology (2026) Cite this article Temporal encoding of signalling dynamics is not just widespread; it offers a fundamental information-theoretic advantage in cellular communication. Recent advances in channel capacity measurement and decoding of second-messenger networks now provide a predictive framework…...
Genome-wide absolute quantification of chromatin looping | Nature Structural & Molecular Biology
1+ day, 10+ hour ago (1728+ words) Nature Structural & Molecular Biology (2026) Cite this article Dekker, J. & Mirny, L. A. The chromosome folding problem and how cells solve it. Cell 187, 64246450 (2024). Yang, J. H. & Hansen, A. S. Enhancer selectivity in space and time: from enhancerpromoter interactions to promoter activation. Nat. Rev. Mol. Cell Biol. 25, 574591 (2024). Popay, T. M. & Dixon,…...
Putting numbers on chromatin looping - Nature Structural & Molecular Biology
1+ day, 8+ hour ago (234+ words) Nature Structural & Molecular Biology (2026) Cite this article Chromatin looping is a fundamental feature of genome organization that contributes to gene regulation and genome stability. Yet how often loops form in living cells has remained difficult to answer. Jusuf et al....
NASA Spaceline Current Awareness List #1, 205 26 June 2026 (Space Life Science Research Results)
1+ day, 17+ hour ago (1086+ words) Astrobiology Web [NASA] The abstract in Pub Med or at the publisher's site is linked when available and will open in a new window. Papers deriving from NASA support: - Carter KJ, Smith JD, Huang AS, Stern C, Kramer LA, Hasan…...