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AllSci Stanford University researchers developed a programmable RNA base-editing system built from human proteins that outperformed established CRISPR-based editors in laboratory comparisons, potentially offering a less immunogenic approach to therapeutic RNA modification. The platform, described in Nature Biotechnology, repurposes the…
The hantavirus outbreak aboard a cruise ship sickened passengers and claimed lives, reminding the world that these rare but deadly viruses remain a serious public health threat. While hantavirus infections are uncommon, severe cases can be fatal and there are…
An in vitro study found that five plant compounds impaired efflux-pump activity and reduced P. aeruginosa PAO1 biofilm formation, with salvianolic acid A producing the strongest effects. Gene-expression analysis supplied an additional level of evidence. Following treatment with salvianolic acid A, qRT-PCR…
An approximately year-long monitoring study found that 365- and 395-nanometre UV-A photographs identified 303 olms from nine Italian caves using stable, naturally occurring skin patterns rather than artificial tags.
Researchers have identified a previously undescribed lineage of Asian horned toad from the Yarlung Tsangpo Grand Canyon in Xizang, China. The discovery is based on three adult female frogs collected at Beibeng Township, Motuo County, Nyingchi City, in May 2025. The…
A Science Bulletin review finds that super-resolution microscopy is shifting from sharper visualization toward validated measurements of molecular organization and dynamics in living systems. Super-resolution microscopy is moving beyond the production of sharper images toward a more demanding goal: making…
They ultimately distinguished 376 consensus OTUs, 137 of which contained lichen-derived sequences. Among those, 23 contained Arthoniales sequences, with 21 newly detected in the study and two taken from earlier GenBank records from Enterographa pallidella and Opegrapha vulgata. Six consensus groups remained paraphyletic. Some…
The study used specimen morphology, diagnostic images and DNA sequences for selected females. The checklist reveals that knowledge of Korean fairyflies developed through scattered revisions and rearing studies rather than a sustained national survey. Jong Cheol Paik’s first 1974 report listed…
Public transcriptomic data also indicated relatively elevated PPR9 expression in embryos, young leaves, shoot apices, root tips and flowers. The researchers began from a T-DNA insertion mutant and used molecular, biochemical and physiological comparisons with wild-type, heterozygous and gene-complemented plants to…
Patient-derived fibroblasts with TFE3-associated neurodevelopmental disorder showed metabolic rigidity, dysfunctional lysosomes, impaired migration and an unstable extracellular-matrix interface. Patient-derived fibroblasts carrying mutations associated with TFE3-associated neurodevelopmental disorder show altered energy metabolism, dysfunctional lysosomes and a destabilized interface with the extracellular…