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Aptamers enable a distinct mode of conformational DNA recognition

Nature Chemistry (2026) Cite this article Reagents and suppliers used in the aptamer selection process have been reported and detailed previously57. Any additional chemicals for SELEX were purchased from regional Sigma-Aldrich suppliers according to local availability and used as received unless otherwise stated. Oligonucleotides were synthesized by Integrated DNA Technologies…

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Bacterial Genome Study Could Lead to Better TB Drugs

Genetic interaction networks, such as the one pictured here, allowed researchers to predict functions for previously uncharacterized genes. (Credit: Rock lab) Rockefeller scientists have created the most comprehensive map to date of how essential genes interact in Mycobacterium tuberculosis (Mtb), the bacterium responsible for tuberculosis (TB). The unprecedented map reveals…

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More in Microbiology