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Lactate From Macrophages Fuels Skin Scarring
12+ hour, 52+ min ago (1650+ words) The pursuit of flawless healing has long been the holy grail of regenerative medicine, yet for millions of patients worldwide, the body's natural response to injury results in the disfiguring and often painful formation of hypertrophic scars. These stubborn lesions,…...
Scientists Create Fly with 140-Million-Year-Old Gene!
15+ hour, 3+ min ago (406+ words) To understand the genetic transformations that have shaped the evolution of fruit flies into their current form, American researchers have revived an ancient gene. This research generally aims to delve deeper into the mechanisms of evolution. No, this isn't a…...
Why Elephant Trunk Whiskers Excel at Touch Sensation
1+ day, 15+ hour ago (1108+ words) In the vast panorama of animal anatomy, the elephant's trunk stands out as a marvel of both strength and sensory finesse. While its rugged exterior might suggest a tool built primarily for brute force, recent scientific investigations have unveiled a…...
Genomic-Driven Breeding Strategies Poised to Fast-Track American Chestnut
1+ day, 16+ hour ago (934+ words) For more than a century, the American chestnut tree stood on the precipice of extinction, devastated by an invasive fungal pathogen that swept through North American forests with relentless ferocity. Today, however, a groundbreaking study employing cutting-edge genomic technologies offers…...
In brief: Co-existing with humans genetically changed bear population
1+ day, 19+ hour ago (500+ words) ALTOONA, Pa. " Critically endangered Apennine brown bears, which reside in central Italy, have significantly reduced genetic diversity compared to other bear populations around the world, according to a team that included Carolyn Mahan, professor of biology and environmental studies at…...
Exploring Germline Mutations and Mosaicism in Liver Disease
1+ day, 19+ hour ago (798+ words) Steatotic liver diseases, which include conditions like metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-related liver disease (ALD), are emerging as critical health challenges globally. Affecting nearly one-third of the world's population, these diseases are not only a major cause…...
Combining Heart Imaging and Proteomics Reveals New Drug Targets for
1+ day, 20+ hour ago (862+ words) Cardiovascular diseases (CVDs) stubbornly persist as the foremost cause of death and disability worldwide, despite decades of advances in prevention and treatment. Conventional risk factors such as hypertension, smoking, and hyperlipidemia only partially explain the complex nature of these diseases....
Rapid Discovery of Cellular Biomolecular Condensates and Proteins
1+ day, 22+ hour ago (883+ words) In the ever-evolving field of cell biology, the ability to identify and understand biomolecular condensates has become paramount. These structures, formed through a process termed liquid'liquid phase separation, play critical roles in regulating cellular processes. However, their dysregulation has been…...
MAPK–CCA1 Loop Boosts Root Nitrate Foraging
1+ day, 23+ hour ago (897+ words) Mitogen-activated protein kinase (MAPK) cascades are renowned as evolutionarily conserved signaling modules essential for myriad cellular processes in eukaryotes, fundamentally orchestrating growth regulation and stress responses. Despite the extensive understanding of MAPK pathways in animal and fungal systems, their nuanced…...
At Last: Science Unveils Their Most Astonishing Secret
2+ day, 16+ min ago (613+ words) Long after birth, a fraction of our own cells carry a quiet maternal signature. This biological duet reflects a phenomenon called microchimerism, where maternal cells persist in offspring. These lingering cells are few, yet their influence appears profound. They illuminate…...